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Qin et al., 2012
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87 Although this rate was slightly lower than that observed in non-surgical controls (1.93 per 1 000 person-years), Cox regression analysis indicated no statistically significant difference in fracture risk (HR = 0.96, 95% CI: 0.831.11), suggesting that VSG may not substantially increase fracture incidence
The most common adverse events were gastrointestinal in nature, consistent with incretin-based therapies, and were generally mild to moderate in severity
That said, I anticipate some price reductions with increased market competition. Hwang said reducing financial barriers to semaglutide and tirzepatide will require efforts from several stakeholders and include public policy changes and reform in commercial insurance coverages