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As these pivotal challenges are incrementally addressed, LONP1 is poised to become a cornerstone therapeutic target for mitochondrial dysfunction-related diseases, potentially redefining existing treatment paradigms
Vitamin C helps "recycle" glutathione back into its active state, while glutathione helps restore vitamin C after it has neutralized a free radical, creating a powerful loop of antioxidant support
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Mutated GST sequences were subcloned into pET-15b, pET-24d, pGEX 4T-1, and pCMV-2B expression vectors, and the mutated constructs were confirmed by DNA sequencing
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