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Quick Answer: GLP-1 receptor agonists are being investigated for potential neuroprotective effects in Alzheimer's disease, but they are not FDA-approved for dementia prevention or treatment
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Obese and diabetic non-human primates 43,44 could be very helpful animal models to analyse the pharmacology of MEDI4166 for both glucose control and LDL-C reduction and might provide additional insights to precisely predict its efficacy in humans
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doi: 10.1242/jcs.115.6.1231 96 ExleyR