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[ref][ref][ref][ref] NLRP3 inflammasome: In addition to studies showing that higher levels of TNF and IL-8 are likely involved in fibromyalgia, studies have also shown that the NLRP3 inflammasome is activated.[ref] (This ties into the Lifehacks section and the clinical trials on supplements targeting NLRP3.) Mast cells: As part of the first line of defense against foreign pathogens and allergens, mast cells are often involved in increasing inflammation in certain tissues
Kalscheuer R, Stveken T, Malkus U, Reichelt R, Golyshin PN, Sabirova JS, Ferrer M, Timmis KN, Steinbchel A
current knowledge, future clinical and translational research questions
In vitro evaluation of the mucoadhesive properties of zinc hyaluronate
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V.DixonB
