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Total calorie intake may fall much lower than women realize
Wingerchuk, D
Participants lost about 7.7 pounds over two months, compared to 4.6 pounds in the placebo group
And to be fair, these types of drugs have been in the making since the early 2000s, according to a 2025 article in Pharmacological Research
The effects of delayed gastric emptying may further compound the risk factors harbored by the obese, diabetic patient: Gastroparesis secondary to diabetes-related autonomic dysfunction Bowel dysmotility from opioids (chronic pain) and prolonged bed-rest Altered oesophageal-gastric anatomy from bariatric surgery Gastric insufflation from overzealous bag-valve ventilation with high PEEP and difficult airway Reduced efficacy of routine antiemetic regime Nausea and vomiting are reported by approximately 50% of patients using GLP-1 agonists, as direct results of reduced gastric motility and activation of central satiety centers
The intellectually honest position is that absence of evidence is not the same as evidence of absence
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