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Separate signaling cascades can also determine an increase of cytosolic Ca 2+ which includes the phosphorylation of PKA after GLP-1 receptor activation, the increase of phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) levels and the mobilization of Ca 2+ stores [33, 36]

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Organic cation transporter 2 activation enhances sensitivity to oxaliplatin in human pancreatic ductal adenocarcinoma

10.1038/ijo.2009.10 36 GrillH

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These observations are usually mild and manageable in research settings but they highlight the importance of monitoring and adjusting research protocols as needed