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However, because hepatotoxicity is a result of complex mechanisms, animal studies must be performed in association with such in vitro experiments
What is missing There is no published human pharmacokinetic study of subcutaneous AOD-9604, no published human topical or intranasal exposure data, no Phase 3 efficacy trial, no long-term safety data beyond 24 weeks, and no published human cartilage or joint outcome data
However, it is always wise to reassess your needs every few months with a healthcare professional to ensure the dosage remains appropriate for your current health status