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Semaglutides are injected by a user and work by activating glucagon-like peptide-1 ( GLP-1 ) receptors, which act by convincing your brain it is full, thus reducing your appetite

Requires ongoing medication use, may be expensive long term, side effects are possible, weight regain may occur after stopping

It makes sense mechanistically, but the hard human clinical proof is limited

Today, TikTok sells it as a $20 face cream

Patients using compounded medications may differ from clinical trial participants in ways that affect outcomes

However, the potentially large target patient population, as well as the increased utilization and high drug costs, are a growing concern for many plan sponsors