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trial, subjects receiving weekly doses of 30 to 60 mcg/kg (roughly 2,000 to 4,000 mcg for an 80 kg adult) showed sustained IGF-1 elevation with no serious adverse events over the study period (Teichman et al., J Clin Endocrinol Metab 2006)

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2024 Dec;32(12):2255-2263

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10.1186/s12916-022-02599-4 179 WHO (2023)

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After three or four freeze-thaw cycles, significant degradation has occurred

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