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During mealtime, the network presented in this study driven by OB GLP-1R may contribute to a decrease in SNS activity, and thus participate in the increase of glucose-induced insulin secretion, in concert with systemic GLP-1 and the GLP-1 dependent neuronal circuitry of the brainstem and hypothalamus recruited under normal physiological circumstances

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Although Wegovy is not approved for Type 2 diabetes, it may be used off-label to manage blood sugar levels, especially in people who may also be overweight or obese