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As an indicative example, without its own effect on normal blood pressure, it counteracts L-NAME hypertension as well as L-arginine hypotension (Sikiric et al., 1997a)

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Vitamin B12 deficiency in over 16s: diagnosis and management (NG239)

NICE guidance recommends intramuscular hydroxocobalamin as first-line treatment for B12 deficiency caused by pernicious anaemia or malabsorption

B12 helps the body convert food into energy, which can support metabolic function

What does not exist in 2026 is a single adequately powered randomised human trial