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The program established a favorable safety profile but the Phase IIb endpoint did not differentiate sufficiently from placebo to support continued development for obesity

doi: 10.3389/fendo.2023.1139444 100 SuzukiCTanidaIOliva TrejoJAKakutaSUchiyamaY

For more significant changes in hyperpigmentation or overall tone, it may take 3 to 6 months of consistent use

Furthermore, the specific inhibition of NNMT by 5-amino-1mq avoids interference with other metabolic enzymes, ensuring the specificity and reliability of experimental results

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