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Arginase 1 deficiency: a treatable form of spastic paraplegia

The correct sequence of the gene of interest (GOI) was confirmed by the Sanger sequencing service of Microsynth

BPC-157 ("Body Protection Compound 157") is a synthetic pentadecapeptide a 15-amino-acid sequence originally isolated as a fragment of a protein found in gastric juice

Evidence for the formation of p -chlorophenyl isocyanate as a reactive intermediate

Replacement of Sec46 by a cysteine or mutation of any of the 3 other amino acids of the catalytic site results in an abrogation or a diminution of GPX4 enzymatic activity [1]

Stimulated by these encouraging results, a novel dual-action polymeric system is proposed for the potential treatment of autoimmune thyroid disease