Pantothenic acid-deficient rats developed damage to the adrenal glands, while pantothenic acid-deficient monkeys developed anemia due to decreased synthesis of heme, a component of hemoglobin
Monitoring the recovery progress dictates the exact end date of the administration period
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At the same time, in old treated animals, the dynamic of oxygen cost of myocardial work did not differ from the untreated group (Figure 4E) that might be due to compensatory mechanisms in myocardium developed with aging