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Because phosphatidylcholine is required in the synthesis of very-low-density lipoprotein (VLDL) particles (see Function), choline deficiency results in impaired VLDL secretion and accumulation of fat in the liver (steatosis), ultimately leading to liver damage
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These treatments are very appealing to individuals with type 2 diabetes and obesity since clinical results show much better weight loss and improved glycemic control
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however, those receiving placebo experienced a similar increase in sleep quality
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