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J Biol Chem 285:2300723018 Idevall-Hagren O, Jakobsson I, Xu Y, Tengholm A (2013) Spatial control of Epac2 activity by cAMP and Ca 2+ -mediated activation of Ras in pancreatic cells

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4150-A UNCOVERING THE BURDEN OF BILIARY TRACT CANCER IN ASIA: GLOBAL BURDEN OF DISEASE STUDY PERSPECTIVES Panisara Fangsaard, Bassett Medical Center, Pojsakorn Danpanichkul, Chiang Mai University, Natchaya Polpichai, Weiss Memorial Hospital, Aunchalee Jaroenlapnopparat, Mount Auburn Hospital/Harvard Medical School, Chawin Lopimpisuth, University of Miami/Jackson Memorial Hospital and Karn Wijarnpreecha, University of Arizona College of Medicine Phoenix, Phoenix, AZ Background: Biliary tract cancer (BTC) is the second most common type of hepatobiliary cancer worldwide and is known for its high mortality rate due to its advanced stage at diagnosis

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