While I understand that cost and access concerns drive people toward compound products, it's crucial to understand that safety issues are real
The answer is complicated, and researchers do not fully understand every mechanism yet
[131] [132] Species from the following genera and the following individual species are known to synthesize B 12 : Propionibacterium shermanii , Pseudomonas denitrificans , Streptomyces griseus , Acetobacterium , Aerobacter , Agrobacterium , Alcaligenes , Azotobacter , Bacillus , Clostridium , Corynebacterium , Flavobacterium , Lactobacillus , Micromonospora , Mycobacterium , Nocardia , Proteus , Rhizobium , Salmonella , Serratia , Streptococcus and Xanthomonas
Ultimately, this results in the modulation of the sleeps architecture and optimization of the various stages of sleep, especially the highly restorative slow-wave sleep (SWS), often referred to as deep sleep or stage 3 sleep [1, 2]
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Targeted nutrients such as omega-3s, vitamin D, magnesium and B vitamins may also play a helpful supporting role alongside a balanced lifestyle