By contrast, when comparing Glp1r Wnt1/ vehicle-treated mice to Glp1r fl/fl vehicle-treated mice, there were no observed DEGs in inguinal WAT or liver (Fig
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However, for more comprehensive effects, it is usually recommended to continue with regular treatments over a span of several months
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The key is to treat optimization like an experiment measure, adjust, and let your physiology guide the protocol changes (if any)
doi: 10.1007/s10545-017-0063-1