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Although GSH-responsive nanomedicine shows great potential, several important areas require further study

Some amount of all the antioxidant enzymes, which may protect spermatozoa from oxidative attack, are also made by the epididymis during storage

During epididymis transport, spermatozoa are vulnerable to intracellular and extracellular ROS attacks and rely on antioxidant scavengers synthesized by the epididymis for protection

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Published trial finding: stopping treatment

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