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Ectopic NRF2 expression was achieved with pLenti-CMV-NFE2L2-Puro (#181919, Addgene)
In short: the cell-culture data establishes biological plausibility for hair-follicle effects
Note: We have no affiliation with Gary Brecka - this article is based on publicly shared information.
In this scenario, a highly virulent disease (like rabies) may be able to cause significant damage or death before the immune system has learned how to effectively fight it
DOI: 10.3389/fphar.2021.627533
Understanding why side effects occur (like hypoglycemia, weight gain, or GI issues) helps us make safer, smarter clinical decisions
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