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The reviewed studies demonstrate that ASD-like behavioral deficits in preclinical models can be modulated through interventions targeting diverse biological systems, including neurotransmission, neuroinflammation, metabolism, and the gut-brain axis
Given that the both GFP and Exe4 knock-ins were performed under same LNP formulations and transfection conditions, digital PCR is expected to provide a reliable measure of Exe4 gene integration
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