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3.2 Necroptosis of tubular epithelial cell in DKD Transcriptomic and single-nucleus RNA sequencing analyses have demonstrated significant enrichment and perturbations of the necroptosis pathway in diabetic kidney tissues, highlighting its core role in driving tubulointerstitial injury (135)

Chambers, S

Inconclusive evidence

Moreover in BALB/c mice, inclusion of GSH in the drinking water decreased viral titer in both lung and trachea homogenates after intranasal inoculation with a mouse-adapted influenza strain A/X-31 ( Our group demonstrated that GSH was able to inhibit also HIV expression in human macrophages at late stages and this was related to the selective decrease of specific glycoproteins, such as gp120, which are notably rich in disulfide bonds (Garaci et al., 1997)

these glutathione molecules can then function again as antioxidants, scavenging reactive oxygen species from the cell

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