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Lncrna tug1/Mir-29c-3p/Sirt1 axis regulates endoplasmic reticulum stress-mediated renal epithelial cells injury in diabetic nephropathy model in vitro

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8 Another portion of APAP (10%) is shunted by hepatic cytochrome CYP 2E1 (to a lesser extent with CYP 1A2 and 3A4) to phase I oxidation, in which a highly reactive toxic metabolite, N -acetyl-para-benzo-quinone imine (NAPQI), is formed

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Despite the low sequence identities, all cytosolic GSTs share a common fold, which is also largely conserved in mitochondrial GSTs (Fig