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The Ozempic label lists only two contraindications: a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and serious hypersensitivity to semaglutide or its excipients

The biologically active forms of GLP-1 are rapidly degraded by DPP-4, resulting in the production of inactive forms of GLP-1 (GLP-1 937 and GLP-1 936 ) [11]

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When comparing three or more groups, one-way analysis of variance (ANOVA) with Tukey's multiple comparisons test was employed