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Red blood cells may be involved in anthracyclines, ifosfamide and its metabolites, topoisomerase I and I/II inhibitor storage, transport, and metabolism

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These findings of increased transcription of cellular adhesion molecules and inhibition of eNOS production of nitric oxide are hallmarks of vascular endothelial dysfunction 47 , providing potential mechanistic insight on the connection between gut microbial reorganization, subsequent PAGln production, and their role in the manifestation of vascular dysfunction

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