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Animal studies have also found that intermittent fasting lowers IGF-1 more effectively than long-term calorie restriction, but other studies have found no difference between the two (32, 33)

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[6] Specifically, in this study conducted by Patrick Jacobs and colleagues, 24 healthy, exercise trained men consumed either 4.5 grams of GPLC or a placebo on two different days separated by one week (double blind, cross-over study design)

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