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46 KahleM.SchferA.SeeligA.SchultheiJ.WuM.AichlerM.et al (2015)

Weeks 5 to 8: The dose is increased to 0.5mg once weekly

While that potency can lead to faster results, it also comes with a more pronounced side effect profile, including things like flushing, nausea, and appetite suppression

You may notice initial slimming and subtle contour changes, but dont expect your final, defined shape right away

How will the GLP-1 telehealth and compounding pharmacies respond

The flip side is that the long half-life also creates relatively stable medication levels between doses, which can actually reduce side effect intensity compared to medications with more dramatic peaks and troughs