The biological age of the heart is consistently younger than chronological age
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If the infusions arent carefully monitored and the fluid drips too quickly, theres a risk of fluid overload, which could affect electrolyte balances and damage the kidneys, brain, and heart
Key findings at the highest dose (12mg weekly): Up to 24% mean body weight reduction over 48 weeks Significant reductions in fasting glucose and insulin resistance markers Meaningful reductions in liver fat content, relevant for participants with metabolic-associated fatty liver disease Once-weekly subcutaneous dosing was generally well-tolerated For context, semaglutide at its approved dose achieves approximately 1517% body weight reduction over 68 weeks
Nausea is a common one, but it seems to subside with use
GIP receptor activation The GIP component enhances the metabolic effects of GLP-1 activation and contributes to improved glucose handling