They act on the same receptor pathway your natural GLP-1 uses, but they are designed to last much longer in the body
Clinical Context & Research Overview Important: Peptide therapy for performance and sleep support should be discussed with a licensed clinician
GLP-1 is an abbreviation for Glucagon-Like Peptide-1 receptor agonist, which is a class of medications commonly used to treat diabetes and to assist with weight loss in patients with or without diabetes
Leah Joseph explains that GLP-1 is a naturally occurring hormone that helps control appetite, regulate blood sugar, and slow digestion
Prescription Topical Treatments Prescription creams or gels are often the first choice for hyperpigmented lips

Ipamorelin Receptor: GHS-R1a | Half-life: ~2 hrs | GH potency: Moderate | Selectivity: High (no cortisol/prolactin) | Appetite effect: Minimal GHRP-6 Receptor: GHS-R1a | Half-life: ~20 min | GH potency: High | Selectivity: Low (elevates cortisol, prolactin, appetite) | Appetite effect: Strong GHRP-2 Receptor: GHS-R1a | Half-life: ~25 min | GH potency: High | Selectivity: Moderate (mild cortisol elevation) | Appetite effect: Moderate Hexarelin Receptor: GHS-R1a | Half-life: ~30 min | GH potency: Highest | Selectivity: Lowest (significant cortisol/prolactin) | Appetite effect: Moderate CJC-1295 no-DAC Receptor: GHRH-R | Half-life: ~30 min | GH potency: Moderate | Selectivity: High (GHRH-pathway only) | Appetite effect: None CJC-1295 DAC Receptor: GHRH-R | Half-life: ~6-8 days | GH potency: Sustained moderate | Selectivity: High | Appetite effect: None Sermorelin Receptor: GHRH-R | Half-life: ~10-20 min | GH potency: Moderate | Selectivity: High | Appetite effect: None Analytical Verification of GHS Peptides Growth hormone secretagogues are among the most frequently counterfeited or under-dosed peptides in the research market due to their popularity and relatively high cost of synthesis
