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accio.com 9Fella Health (April 2026)
Multiple randomized controlled trials including the SUSTAIN series demonstrate that GLP-1 therapy improves HOMA-IR (a measure of insulin resistance) and fasting insulin levels independent of weight loss alone
The SURMOUNT-1 Three-Year Study The longest completed tirzepatide trial to date is the SURMOUNT-1 study, which followed participants for 176 weeks, approximately three and a half years
Short acting agents may be best suited for patients with type 2 diabetes that includes exaggerated postprandial glucose excursions , and for co-administration with basal insulin therapy (Guo, 2016
Patient education remains critical throughout treatment
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