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People with a specific variant of the MTHFR (methylenetetrahydrofolate reductase) gene have an impaired ability to break down and use folate

For deficiency without neurological involvement or for borderline levels, oral supplementation with high-dose cyanocobalamin (1000-2000 mcg daily) is often effective, as approximately 1% of an oral dose is absorbed through passive diffusion even in the absence of intrinsic factor

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Official product specifications

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The compound is not a supplement, cosmetic or therapeutic substance and any misuse outside of research applications is against regulatory guidelines and institutional policies