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While cagrilintide activates amylin receptors to reduce appetite and slow gastric emptying, semaglutide stimulates GLP-1 receptors to enhance insulin secretion, suppress glucagon, and promote satiety through distinct neural pathways

This approach theoretically prevents tolerance development and allows natural NNMT function to reset periodically

Following the treatment, the body takes over with its natural waste removal mechanisms

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Lactate-producing bacteria, such as Lactobacillus and Bifidobacterium , play a key role in the human gut microbiota and have shown effectiveness in alleviating IBD by improving intestinal permeability, reducing inflammation, and importantly, influencing the composition of the gut microbial community [244, 245]