tirzepatide's exclusivity runs through 2033
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A double-blind, randomized phase 2 study comparing various doses (1, 5, 10, 15 mg) of once weekly tirzepatide, dulaglutide (1.5 mg) and placebo, in patients with T2DM, showed tirzepatide was superior on weight loss and glucose-lowering compared to both dulaglutide and placebo [52]
The research also showed that most side effects were related to the speed of dose increases
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This long half-life means the drug maintains therapeutic levels between injections, and a single missed dose does not cause dramatic fluctuations in blood levels