Whether declining MOTS-c is a cause or consequence of this deterioration is still being resolved, but the correlation is striking enough that some researchers have proposed plasma MOTS-c as a biomarker of mitochondrial vitality and metabolic age
Presented for research literature review only Koberstein R (1976)
Dihexa's oral activity is attributed to its small size, modified N-terminus (hexanoic acid cap), and hydrophobic character
Genetic predisposition can modulate cellular sensitivity to apoptosis, and multiple regulatory factors are involved, including inflammatory mediators (IFN-, IL-2, IL-1), TSH, and anti-TPO antibodies
The clinical consequence ranges from local inflammation through to systemic hypersensitivity and antibody formation
- , BPC-157 FAK, [12]