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Indeed, NRF2 was found constitutively active in intestinal stem cell (ISC) in , and KEAP1-mediated NRF2 repression was required for ISC proliferation

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10.1038/s41586-021-03539-7 80

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The peptide also increases elastin production, which can improve the texture and pliability of stretch marked areas

In addition, pathogen challenge elicited particularly dynamic responses of GSTF8: by 2 h after inoculation the corresponding transcript was already significantly up-regulated and the post-translational protein modifications detected were specific for incompatible interactions (Jones et al., 2004)