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It binds to both GIP and GLP-1 receptors, which are G-protein-coupled receptors expressed in pancreatic beta cells, the gastrointestinal tract, adipose tissue, and the central nervous system
194 Despite these potential genetic correlates, variants account for only 25% to 44% of the heritability of IR
doi: 10.3390/cancers14133059
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BMC Genomics 13 , 655 (2012)
GLP-1 receptor agonists-medications like Ozempic, Wegovy, Mounjaro, and Zepboundmimic a natural gut hormone that signals fullness to the brain while slowing digestion and boosting insulin release
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