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These behavioral benefits are underpinned by its marked ability to induce spinogenesis and promote functional synaptogenesis in hippocampal neurons, highlighting its potential as a robust procognitive and antidementia agent [2]

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Current approaches include: Continuous Use Approach: Based on clinical trials that used continuous daily administration for 12-24 weeks without scheduled breaks

Keap1, PINK1, Parkin, and LC3 expression increased and Nrf2, NQO1, HO-1, and p62 expression decreased in oxidatively injured cells

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