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Of note, gallbladder dyskinesia becomes evident both in vitro in smooth muscle strips, in the animal model of early cholelithogenesis [69] and in cholesterol gallstone patients with small stones [70, 71] not able to mechanically block the gallbladder contractility, as shown in the animal model [72]

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However, the majority of adverse events in both treatment groups were mild-to-moderate GI events, with the most common being transient nausea [39]

le Roux CW, Davies M, Frias JP, Jensen C, Nrkjr Laursen P, Lingvay I, Machineni S, Varbo A, Wilding JPH, Perreault L