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The application of most ferroptosis-targeting agents in retinal diseases is still in the preclinical stage of new drug development, and there are no clinical trials yet

However, research suggests slightly more people discontinue Wegovy than Trulicity due to adverse events, with around 13% of patients stopping Wegovy because of adverse events, compared to around 9% on Trulicity

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Shao T, Hsu R, Rafizadeh DL, Wang L, Bowlus CL, Kumar N, Mishra J, Timilsina S, Ridgway WM, Gershwin ME (2023) The gut ecosystem and immune tolerance

2024), which supports TAAR1 agonism in ASD to potentially improve mitochondrial respiration