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In brief, HCT116 cells were infected with the GeCKO v1 human CRISPR knockout pooled library using lentiviral transduction at a multiplicity of infection of 0.3, and populations stably expressing gRNAs were selected for using puromycin and expanded for 8 days to allow for essential gene drop-out
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This process involves an increase in single-nephron glomerular filtration rate in the remaining nephrons to compensate for the loss of function
Pharmacovigilance studies indicate that GLP-1RAs, with the exception of albiglutide, demonstrate potential associations with pancreatic cancer risk, particularly evident in exenatide-treated patients who exhibit elevated cancer incidence rates
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Kidney Res Clin Pract 41(Suppl 2):S74S88
Verified peptides are research compounds with documented third-party purity testing typically via HPLC-MS analysis that confirms compound identity and purity percentage on a per-lot basis
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