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Or wait at least 30 minutes between applications to allow each ingredient to absorb and stabilize before adding the next
Clnica 72 (6), 380385
Retinol works by speeding up cell turnover, which can improve texture and reduce fine lines
GHK-Cu also stimulates both collagen synthesis and matrix metalloproteinases that break collagen down, so unbalanced or excessive use could in principle disrupt extracellular-matrix homeostasis
The point of loading is not to feel a repeated boost, it is to bring low levels back up to a normal range before switching to a slower schedule
Is GHK-Cu Safe to Use
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