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In addition to its activity against hyperglycemia, DPP-4i has shown beneficial cardiovascular effects including cardioprotective action, endothelial protection, and an anti-hypertensive effect

doi: 10.1038/s41418-021-00859-z 23 ChenXYuCKangRKroemerGTangD

Dual GIP/GLP-1 receptor agonists like tirzepatide target two incretin pathways simultaneously, potentially offering advantages over single GLP-1 agonists

Luminescence-based activity assays suggest that this cleavage site shift evolved during higher-stringency rounds of selection on procaspase-1

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Based on prescription numbers, it is clear that more and more people are using these drugs