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Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes
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The increased oxidative load disrupts the bodys intrinsic antioxidant defense systems, such as manganese superoxide dismutase (MnSOD) and glutathione peroxidase (GPx), resulting in lipid peroxidation, DNA damage, and the activation of pro-apoptotic pathways, including p53 and BAX 5,7
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