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This result, together with the fact that intra-Nacc injection of proteasome inhibitors prevents the consolidation of morphine place preference, strongly suggests that UPS activity in the Nacc is involved in drug-context association rather than non-associative motivational effects of opioids

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This bioavailability gap means oral dosing requires higher amounts to achieve equivalent systemic exposure

A negative correlation was noted between serum vitamin D levels and the prevalence of bronchial asthma (224, 225)