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Two patterns are worth calling out because they are predictable rather than alarming
Tirzepatide has not been studied in patients with severe gastrointestinal disease, including severe gastroparesis, and is therefore not recommended in these patients
doi:10.3349/ymj.2003.44.2.227 Tajiri J, Higashi K, Morita M, Umeda T, Sato T
Diabet Med 32(6):725737 Khunti K, Seidu S, Kunutsor S, Davies M (2017) Association between adherence to pharmacotherapy and outcomes in type 2 diabetes: a meta-analysis
177 One particularly promising avenue involves metabolic disruption: depletion of intracellular ATP, which powers transporter function, has been shown to impair drug efflux
These approaches will not be suitable for everyone and are presented here only to help you generally understand what to expect when beginning drug therapy
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