IL-1 is known to disrupt long-term potentiation and synaptic transmission [34] while TNF- alters postsynaptic AMPA receptor regulation [35], thereby impairing synaptic homeostasis
They also have many potential side effects like swelling, headaches and increased cancer risk
But it explains why two people of similar weight and health status can have dramatically different experiences on the same dose
Preclinical studies show synergy with chemotherapeutics, but human trials are limited by variable bioavailability
Hims & Hers, which recently launched a weight loss program and now offers access to GLP-1 injections, has also begun publishing blog posts delving into the potential side effects of GLP-1 drugs
(Of course, these drugs can have side effects of their own.) Common ones include: Metformin (which can also cause diarrhea) Empagliflozin ( Jardiance ) Glimepiride (Amaryl) Sitagliptin (Januvia) Each drug works differently to treat diabetes