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When blood vessels constrict, the heart has to pump harder to move blood through the body, which can result in an increased heart rate

But whats unique about GLP-1 use is that these drugs can potentially simulate rapid weight loss, which could worsen muscle loss compared to more gradual weight loss, Pinto says

Studies show caffeine stimulates thermogenesis and may increase fat oxidation by 311 percent, but this occurs through sympathetic nervous system activation, not GLP-1 pathways

Key Takeaway: Your weight loss journey is a marathon, not a sprint

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Our Take You're 90 minutes into a long ride and your stomach is already talking back