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For most peptides, the PK and PD timescales are tightly linked: when serum concentration falls, effect diminishes

Evaluation of the efficacy and safety of amustaline/glutathione pathogen-reduced RBCs in complex cardiac surgery: the Red Cell Pathogen Inactivation (ReCePI) studyprotocol for a phase 3, randomized, controlled trial

Shaking creates foam and can denature the peptide

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A peptide is simply a short chain of amino acids

The bioavailability of ocular drugs is less than 5% owing to factors such as rapid tear turnover and the presence of the corneal barrier