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Fiber supplements should be introduced gradually and taken with sufficient water to avoid worsening gastrointestinal discomfort

This sensitivity is essential for the bodys ability to respond appropriately to the presence of stool in the rectum, thus preventing involuntary leakage and maintaining continence

Participants provided written informed consent to the study prior to any study procedures

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This research has helped clarify the biological mechanisms underlying sarcoma progression and supported the development of molecularly defined disease categories