Repeat determinations of iron and folic acid may reveal a complicating illness that might inhibit the response of the marrow
B12 shots can go into muscles, under the skin, or through veins
That being said, neither study specifically states how much one must take of vitamin B12 (or folate) for their blood serum levels to register as either "very high" or "extremely high." For that reason, although vitamin B12 (and folate) supplementation are important during pregnancy, it's best to look to your healthcare provider for guidance
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Most importantly, anyone who has signs and symptoms of a vitamin B12 deficiency or pernicious anemia should consult a doctor
Nonetheless, it should be used within a certain timeframe as recommended by the pharmacy (often 28 days after first puncture, per general guidelines for multi-dose vials, unless otherwise specified)